Maciej CegÅ‚owski delves deeply into a fascinating question: if scurvy was solved in 1747, why did it plague Robert Falcon Scott’s 1911 expedition to the South Pole?

… in the second half of the nineteenth century, the cure for scurvy was lost. The story of how this happened is a striking demonstration of the problem of induction, and how progress in one field of study can lead to unintended steps backward in another.

An unfortunate series of accidents conspired with advances in technology to discredit the cure for scurvy. What had been a simple dietary deficiency became a subtle and unpredictable disease that could strike without warning. Over the course of fifty years, scurvy would return to torment not just Polar explorers, but thousands of infants born into wealthy European and American homes. And it would only be through blind luck that the actual cause of scurvy would be rediscovered, and vitamin C finally isolated, in 1932.

03/08/10 @ 10:09 PM

Who knew H1N1 would make for such a good photo gallery. Check the agony and the eggstacy.

11/19/09 @ 12:56 AM

Wired is running a great story on why it sucks for all of us that the anti-vaccine movement continues to gather steam. Long and fascinating, but if you’re pressed for time here’s my crude, one-sided, nutshell attempt:

Consider: In certain parts of the US, vaccination rates have dropped so low that occurrences of some children’s diseases are approaching pre-vaccine levels for the first time ever. And the number of people who choose not to vaccinate their children (so-called philosophical exemptions are available in about 20 states, including Pennsylvania, Texas, and much of the West) continues to rise.

That may not sound like much, but a recent study by the Los Angeles Times indicates that the impact can be devastating. The Times found that even though only about 2 percent of California’s kindergartners are unvaccinated (10,000 kids, or about twice the number as in 1997), they tend to be clustered, disproportionately increasing the risk of an outbreak of such largely eradicated diseases as measles, mumps, and pertussis (whooping cough). The clustering means almost 10 percent of elementary schools statewide may already be at risk.

Ah, risk. It is the idea that fuels the anti-vaccine movement — that parents should be allowed to opt out, because it is their right to evaluate risk for their own children. It is also the idea that underlies the CDC’s vaccination schedule — that the risk to public health is too great to allow individuals, one by one, to make decisions that will impact their communities. (The concept of herd immunity is key here: It holds that, in diseases passed from person to person, it is more difficult to maintain a chain of infection when large numbers of a population are immune.)

All you have to do to get the measles is to inhabit the airspace of a contagious person within two hours of them being there.

The frightening implications of this kind of anecdote were illustrated by a 2002 study published in The Journal of Infectious Diseases. Looking at 3,292 cases of measles in the Netherlands, the study found that the risk of contracting the disease was lower if you were completely unvaccinated and living in a highly vaccinated community than if you were completely vaccinated and living in a relatively unvaccinated community. Why? Because vaccines don’t always take. What does that mean? You can’t minimize your individual risk unless your herd, your friends and neighbors, also buy in.

P.S. The immunocompromised are particularly hosed by the unvaccinated.

10/21/09 @ 07:45 AM

From the department of “sounds too good to be true but a guy can dream, can’t he?”, comes news that there might be hope for a one-time flu shot which not only works against your garden variety flu bugs, but some of the known pandemic-grade varieties as well.

04/01/09 @ 05:41 PM

Hi

I'm Jim Biancolo, and this is stuff I found interesting that I thought you might like too. Here are some of my favorites if you want to start there. Mostly I link to other people, but some stuff is mine, like:

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I am loving Instapaper, and use if to sock away stuff to read. Here are a bunch of articles I read recently and liked.

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